A new study reveals the function of the unique nerve endings in the clitoris and penis, first discovered in the 19th century

A recent study highlights the significance of nerve endings in the penis and clitoris during sexual activity. These nerve endings, called Krause’s balls, detect vibrations and light touch in the genitals, leading to sexual pleasure. The research, published in the journal Nature, may contribute to the development of treatments for sexual disorders in the future.

Krause’s balls were first discovered in humans over 160 years ago and are found in areas where the skin and mucous membranes meet, such as the genitals, lips, and eyes. These structures play a crucial role in sexual sensations and are sensitive to vibrations of 40-80 hertz, a range commonly encountered during intimate skin contact and used in sex toys.

Studies on mice have shown that Krause’s balls are structurally similar to human balls and are essential for sexual responsiveness. Male mice lacking these nerve endings exhibited reduced sexual ability, while female mice showed decreased willingness to engage in sexual activity. This indicates that in males, the sense of smell may play a more significant role in arousal, while in females, genital touch is crucial.

Research also revealed that Krause’s balls are 15 times more abundant in the clitoris than in the penis, explaining the organ’s heightened sensitivity. The absence of these nerve endings in the vagina raises questions about how female genital structures influence sexual satisfaction and sensation diversity compared to males. Furthermore, the study identified the ion channel Piezo2 as crucial for sexual pleasure and mating.

Understanding the mechanisms behind sexual arousal and satisfaction may pave the way for better treatments for sexual disorders in the future. The findings from this study shed light on the intricate role of nerve endings in sexual pleasure and highlight the importance of these structures in sexual functioning.